Richard Gorlick Selected Research

palifosfamide lysine

9/2009

Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma.

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Richard Gorlick Research Topics

Disease

146	Neoplasms (Cancer) 01/2022 - 02/2002
119	Osteosarcoma (Osteogenic Sarcoma) 01/2022 - 03/2002
23	Ewing Sarcoma (Sarcoma, Ewing) 12/2021 - 07/2003
22	Sarcoma (Soft Tissue Sarcoma) 11/2021 - 07/2003
18	Neoplasm Metastasis (Metastasis) 10/2020 - 07/2002
16	Neuroblastoma 01/2020 - 06/2006
13	Leukemia 02/2021 - 07/2002
13	Rhabdomyosarcoma 01/2020 - 02/2002
12	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2017 - 09/2003
8	Necrosis 10/2016 - 11/2003
6	Glioblastoma (Glioblastoma Multiforme) 01/2014 - 06/2008
5	Wilms Tumor (Wilm's Tumor) 01/2020 - 05/2008
5	Colorectal Neoplasms (Colorectal Cancer) 05/2009 - 07/2002
4	Rhabdoid Tumor (Rhabdoid Tumors) 01/2019 - 05/2008
3	Breast Neoplasms (Breast Cancer) 01/2016 - 10/2009
3	Disease Progression 07/2015 - 09/2003
2	Melanoma (Melanoma, Malignant) 01/2022 - 01/2016
2	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 01/2022
2	Carcinoma (Carcinomatosis) 12/2021 - 06/2008
2	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 02/2021 - 09/2002
2	Left Ventricular Dysfunction 01/2019 - 10/2016
2	Cardiotoxicity 01/2019 - 07/2012
2	Neutropenia 01/2019 - 02/2013

Drug/Important Bio-Agent (IBA)

38	N- propyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (PPTP)IBA 01/2017 - 12/2007
17	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
17	Methotrexate (Mexate)FDA LinkGeneric 10/2016 - 07/2002
15	Pharmaceutical PreparationsIBA 12/2021 - 08/2003
14	Messenger RNA (mRNA)IBA 01/2022 - 03/2002
12	Biological ProductsIBA 10/2021 - 08/2010
8	Immunoconjugates (Immunoconjugate)IBA 01/2022 - 01/2016
8	Cisplatin (Platino)FDA LinkGeneric 10/2016 - 03/2005
7	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 03/2005
6	RNA (Ribonucleic Acid)IBA 01/2022 - 05/2009
6	Membrane Proteins (Integral Membrane Proteins)IBA 01/2022 - 10/2004
6	Vincristine (Oncovin)FDA LinkGeneric 12/2021 - 12/2007
6	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 04/2004
6	Phosphotransferases (Kinase)IBA 01/2020 - 06/2008
6	Insulin-Like PeptidesIBA 01/2014 - 03/2003
6	Reduced Folate Carrier ProteinIBA 01/2011 - 02/2003
5	Topotecan (Hycamtin)FDA LinkGeneric 12/2021 - 05/2010
5	LigandsIBA 12/2019 - 05/2008
5	Ifosfamide FDA LinkGeneric 10/2016 - 01/2008
5	EnzymesIBA 01/2016 - 02/2002
5	AntibodiesIBA 01/2014 - 09/2008
5	Sirolimus (Rapamycin)FDA Link 05/2012 - 04/2008
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2009 - 09/2004
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2021 - 12/2007
4	Insulin (Novolin)FDA Link 01/2021 - 04/2014
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2013
4	eribulin FDA Link 10/2020 - 08/2013
4	Monoclonal AntibodiesIBA 12/2016 - 05/2007
3	Interleukin-12 (IL 12)IBA 01/2022 - 01/2019
3	VimentinIBA 01/2022 - 01/2019
3	CytokinesIBA 01/2022 - 09/2015
3	Transcription Factors (Transcription Factor)IBA 12/2021 - 07/2002
3	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2021 - 05/2008
3	Irinotecan (Camptosar)FDA LinkGeneric 01/2020 - 02/2002
3	glembatumumab vedotinIBA 11/2019 - 10/2014
3	Etoposide (VP 16)FDA LinkGeneric 10/2016 - 01/2008
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 03/2004
3	ProdrugsIBA 06/2015 - 09/2009
3	Trastuzumab (Herceptin)FDA Link 01/2014 - 01/2010
3	ParaffinIBA 01/2013 - 05/2007
3	Imatinib Mesylate (Gleevec)FDA Link 01/2013 - 05/2008
3	Cytotoxins (Cytolysins)IBA 04/2012 - 02/2005
3	Immunoglobulin G (IgG)IBA 07/2010 - 06/2006
3	Thymidylate SynthaseIBA 05/2009 - 06/2003
3	Leucovorin (Folinic Acid)FDA Link 05/2009 - 02/2005
2	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2022
2	InterferonsIBA 01/2022 - 06/2013
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022 - 01/2020
2	Epidermal Growth Factor (EGF)IBA 01/2021 - 11/2009
2	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 01/2021 - 02/2012
2	Cell Surface ReceptorsIBA 01/2021 - 02/2012
2	Insulin ReceptorIBA 01/2021 - 02/2012
2	S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA 10/2020 - 01/2018
2	Sorafenib (BAY 43-9006)FDA Link 01/2020 - 12/2010
2	Glycoproteins (Glycoprotein)IBA 11/2019 - 01/2016
2	AnthracyclinesIBA 01/2019 - 07/2012
2	Growth Factor ReceptorsIBA 01/2019 - 07/2010
2	Dexrazoxane (Zinecard)FDA LinkGeneric 01/2019 - 07/2012
2	LipidsIBA 12/2017 - 04/2013
2	Antineoplastic Agents (Antineoplastics)IBA 10/2016 - 02/2002
2	purineIBA 03/2016 - 03/2002
2	ImmunosorbentsIBA 01/2016 - 02/2014
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2016 - 04/2014
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2016 - 06/2006
2	Taxoids (Taxanes)IBA 11/2015 - 07/2015
2	Antimitotic AgentsIBA 07/2015 - 08/2013
2	Temozolomide (Temodar)FDA LinkGeneric 02/2015 - 05/2013
2	talazoparibIBA 02/2015 - 01/2015
2	GD2 gangliosideIBA 01/2015 - 02/2014
2	Tyrosine Kinase InhibitorsIBA 01/2015 - 10/2009

Therapy/Procedure

42	Therapeutics 01/2022 - 02/2003
40	Drug Therapy (Chemotherapy) 12/2021 - 08/2002
4	Induction Chemotherapy 10/2016 - 07/2003
3	Radiotherapy 06/2015 - 05/2013
2	Intravenous Infusions 01/2022 - 02/2013
2	Radioimmunotherapy 01/2019 - 12/2016
2	Limb Salvage 01/2017 - 01/2004